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Senior Scientist Antibody Discovery

Cambridgeshire   •  Negotiable  •  Permanent, Full time


Senior Scientist Antibody Discovery and Protein Engineering

Competitive Salary and Package

Cambridge

Perm Full time

CPL are currently looking for a highly driven and motivated candidate to join our expanding team in the Cambridge area. Our client is in the process of bringing their Antibody Discovery in house, you will be key in driving and executing their antibody engineering activities across the early stages of antibody discovery programs.

This opportunity will also contribute to the design of antibody discovery campaigns, molecule formats (including bispecific), sequence analysis and design, molecular biology and antibody production at CROs and in-house QC.

You will work closely with 2 experienced Program leads to execute functional assays and help shape the future of the clients Antibody discovery.

Key Responsibilities

· To lead the sourcing, production, design, QC and assessment of antigens, reagents and program tools using ELISA/Octet/SDS PAGE/SEC HPLC/Western Blot, including benchmark/tool antibodies and required cross species antigens.

· Undertake antibody sequence analysis, identifying antibody liabilities, framework mutations and interpret the data for antibody development.

· To set up key supporting assays to facilitate program development, ELISA/Octet/cELISA and utilise these assays during the programs to QC and assess antigens and antibodies.

· Responsibility for antibody affinity studies and program protein assessment and ligand binding QC Octet/Biacore. Liaise with external partners (CROs) if required to deliver to time and budget.

· Undertake additional lab-based experiments as required to drive forward program delivery, supporting the wider project team to meet program deadlines and milestones. Use a flexible approach when working within the antibody discovery team to achieve program goals in a timely manner. Be the antibody discovery functional lead for the clients program(s).

· Apply teamwork and adaptability to go beyond the designated scope when required to deliver project goals set by the head of antibody discovery (supported by the program lead)

· To identify risks and issues arising on managed activities (timeline, resource, or budget impacts) and to create contingency plans in collaboration with the Head of Antibody Discovery and project teams.

· Present data clearly to project teams and ensure reporting of program progression, data readouts and status to the relevant audiences (internal and external stakeholders as required).

Please apply within or send your CV to mark.bathe@cpl.com

  • Agency: Cpl Life Sciences
  • Reference: JO-2305-516770
  • Posted: 24th May 2023
  • Expires: 21st June 2023

Cpl Life Sciences

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