(Senior) Scientist - Discovery Pipeline
Permanent
Cambridge
Competitive
SRG is delighted to be partnering with an exciting start-up biotech company based in the Cambridge area. They are currently looking for a highly motivated Scientist to join the discovery team where you will be contributing to the development of novel TCR Therapeutics. This is a fantastic opportunity for someone looking to work in a dynamic environment and rapidly expand their knowledge and skillset.
Key Responsibilities:
- Intellectual leadership of the use of high-through-put cell sorting and single cell sequencing to efficiently recover human TCRs
- Designing and implementing protocols to specifically recover T cells
- Sorting/screening using a multi-parameter flow cytometer to sort and analyse desired cell populations
- Designing panels to further dissect T cell subsets
- Development and application of LIBRA-Seq/Beam-Seq (10X Genomics) for TCR discovery
- Contributing to the development of microfluidics based single cell technology for TCR discovery
- Development, QC and use of in-house manufactured probes by working with protein & technology development teams
- Library construction for PCR/NGS processes
- Establishment, review, and updates of SOPs
Ideal Candidate:
- A Ph.D. (or equivalent experience) in Immunology/Cell Biology/Molecular Biology or similar with a strong flow core/immune-assays background
- Several years of postdoctoral experience in an academic or industry setting
- Extensive experience in designing and testing multi-parameter panels for analysis and sorting
- Extensive experience with flow analysis software (e.g. FACSDiva, FlowJo)
- Significant practical laboratory experience working with primary and immortalised mammalian cell lines
- Experience in design and setting up Microfluidics based assays
- Experience in single cell technology and library preparation (desirable)
- Demonstrated skills in trouble shooting and technology development
If you are interested in discussing the role further, then please reach out to me at / 02039379660
Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.
You must have the right to work in the UK. Learn more
- Agency: SRG
- Reference: BBBH126861
Website: SRG
- Posted: 14th March 2023
- Expires: 11th April 2023
