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(Senior) Scientist - Pipelines

Cambridgeshire   •  £45000 - £55000 per annum  •  Permanent, Full time

(Senior) Scientist - Discovery Pipeline




SRG is delighted to be partnering with an exciting start-up biotech company based in the Cambridge area. They are currently looking for a highly motivated Scientist to join the discovery team where you will be contributing to the development of novel TCR Therapeutics. This is a fantastic opportunity for someone looking to work in a dynamic environment and rapidly expand their knowledge and skillset.

Key Responsibilities:

  • Intellectual leadership of the use of high-through-put cell sorting and single cell sequencing to efficiently recover human TCRs
  • Designing and implementing protocols to specifically recover T cells
  • Sorting/screening using a multi-parameter flow cytometer to sort and analyse desired cell populations
  • Designing panels to further dissect T cell subsets
  • Development and application of LIBRA-Seq/Beam-Seq (10X Genomics) for TCR discovery
  • Contributing to the development of microfluidics based single cell technology for TCR discovery
  • Development, QC and use of in-house manufactured probes by working with protein & technology development teams
  • Library construction for PCR/NGS processes
  • Establishment, review, and updates of SOPs

Ideal Candidate:

  • A Ph.D. (or equivalent experience) in Immunology/Cell Biology/Molecular Biology or similar with a strong flow core/immune-assays background
  • Several years of postdoctoral experience in an academic or industry setting
  • Extensive experience in designing and testing multi-parameter panels for analysis and sorting
  • Extensive experience with flow analysis software (e.g. FACSDiva, FlowJo)
  • Significant practical laboratory experience working with primary and immortalised mammalian cell lines
  • Experience in design and setting up Microfluidics based assays
  • Experience in single cell technology and library preparation (desirable)
  • Demonstrated skills in trouble shooting and technology development

If you are interested in discussing the role further, then please reach out to me at / 02039379660

Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.

You must have the right to work in the UK. Learn more

  • Agency: SRG
  • Reference: BBBH126861
  • Posted: 14th March 2023
  • Expires: 11th April 2023


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