Research Associate / Scientist - Protein Science
Permanent
Cambridge
Competitive
SRG is delighted to be partnering with an exciting start-up biotech company based in the Cambridge area. They are currently looking for a highly motivated research associate/scientist to join the protein science teams where you will be contributing to the development of novel TCR Therapeutics. This is a fantastic opportunity for someone looking to work in a dynamic environment and rapidly expand their knowledge and skillset.
Key Responsibilities:
- Perform DNA cloning and prepare DNA constructs for transfections.
- Express novel TCR formats in HEK293 and CHO cells in small, medium and large scale
- Perform protein purification and ensure proteins are of high-quality using protein analytical and assay techniques (SDS-PAGE, HPLC-SEC, ELISA)
- Maintain and establish cell lines required for protein production.
- Provide high-quality protein material to the downstream protein characterisation team.
- Support protein team in functional and biophysical characterisation
- Analyse and present work/data in group meetings and produce accurate scientific reports and SOPs.
- Maintain up-to-date and accurate laboratory record of all experimental activities.
Ideal Candidate:
- An BSc/MSc (or equivalent) in a life-sciences or related subject for the Research Associate level with at least 2 years of industry experience OR a PhD (or equivalent) in a life-sciences or related subject for the Scientist level
- Significant experience with molecular biology techniques such as DNA cloning and protein expression
- Hands-on experience in protein production in mammalian cells such as protein-based biologics
- Experience with protein expression in E. coli and troubleshooting difficult expression would be highly desirable.
- Practical knowledge of the AKTA purification platform and using conventional chromatography resins e.g. ion exchange
- Good working knowledge of a range of methodologies to characterise proteins.
- Knowledge and/or experience in antibody or soluble TCR development would be highly desirable.
If you are interested in discussing the role further, then please reach out to me at / 02039379660
Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.
You must have the right to work in the UK. Learn more
- Agency: SRG
- Reference: BBBH126856
Website: SRG
- Posted: 14th March 2023
- Expires: 11th April 2023
