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Research Scientist – Downstream Process Development and Protein Chemistry

Nottingham, Nottinghamshire NG1 1GF   •  £30K-£35K depending on experience  •  Permanent, Full time


Phenotypeca is looking for a Research Scientist with extensive experience in protein purification and characterisation / bioanalysis to join their growing team developing vaccine, diagnostics and therapeutic protein production processes.

The Role:

As the perfect candidate, you will be strongly motivated to play an integral part in developing the next generation of yeast bioprocess technology for industrial biologics manufacturing. You'll have a thirst to discover new things about this safe and reliable eukaryote, using cutting-edge techniques and working collaboratively with established experts in the field. With great development prospects, you will work as part of a multi-disciplinary team responsible for meeting corporate goals to optimise R&D scale biologics processes for our customers and partners.

You will be an integral part of R&D scale downstream process development projects and actively support product characterisation / bioanalysis to inform upstream process development and optimal strain selection. As an ideal candidate, you will have outstanding protein purification and characterisation skills needed to develop R&D processes ready for scale-up to clinical and cGMP manufacturing. The role will include liaison with project partners, service providers and stakeholders, as well as the development and exemplification of the company's patent approach.

An important element of the role is ensuring a safe working environment is maintained at all times through the implementation of Phenotypeca procedures and guidelines as well as the preparation and maintenance of EH&S documentation and SOPs.

You will have:

  • A life-science PhD with 2+ years relevant postdoctoral experience, or equivalent.
  • Experience in protein purification and protein chemistry, especially where relevant to cGMP biologics manufacturing.
  • Industrial experience in customer-centric projects and research commercialisation would be an advantage.
  • Excellent team-working and communication skills and a proactive approach to problem-solving.
  • Effective time-management skills and the ability to work to deadlines.
  • Ideally, you will also have experience in laboratory workflow automation and handling large data sets, such as in a machine learning project.

Applicants with some of these skills, e.g. with experience in protein purification or protein chemistry / characterisation, are also invited to apply.

In return, we offer a competitive salary based on experience, skills and qualifications. 24 days holiday plus bank holidays (England). Additional benefits include a pension and a potential employee share option.

This role will be based in BioCity Nottingham.

Normal Working Hours: 7.5hrs per day between 8 am and 6 pm Monday to Friday*.

About us:

Phenotypeca is a rapidly growing yeast research and commercially focussed Biofoundry business, currently working on bioprocess development for vaccines, diagnostics and therapeutic protein production.

We have the world's most extensive collection of Saccharomyces cerevisiae strains for industrial recombinant protein production, comprising up to a billion genetically distinct strains. Phenotypeca optimises biologics production strains to make treatments more affordable and available at the right quality to those who need them.

We are a focussed yet fun company driven by performance, has strong business ethics and embraces scientific excellence. Above all, we put our customers first and want our people to be happy and healthy.

How to apply:

If you feel you have what it takes to join our life-changing mission, please submit your CV and Covering letter via the 'Apply' link below.

If you'd like to find out more about this opportunity before you apply, please call Simeon Ractliffe on 0115 698 0303 or email: phenotypeca@n2resourcing.com

We process your application and any enquiries in a safe and strictly confidential manner. We aim to respond to you within 2 working days.

Phenotypeca is an Equal Opportunities Employer.

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Related skills: Biochemistry, Biology, Chemistry, Life Science, Laboratory, Manufacturing


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  • Employer: Phenotypeca
  • Contact: Simeon Ractliffe
  • Phone: 0115 698 0303
  • Updated: 20th June 2022
  • Expires: 18th July 2022

Phenotypeca

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