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Biochemical Engineer

Oxfordshire   •  £30000 - £40000 per annum  •  Permanent, Full time


A growing start-up has an exciting opportunity for a Biochemical Engineer to join its team. As biochemical engineer, you will be developing the manufacturing process to produce tissue at large-scale. You will ideally be educated to PhD in Chemical Engineering, or a related subject, and have experience in upstream bioprocessing and in in designing, developing and operating bioreactors.

Position summary:

As a Biochemical Engineer in the Bioprocessing team you will be tasked with developing the manufacturing process to produce tissue at large-scale. Your duties will include:

  • Design, build and operate bioreactor technology at the bench-scale to enable efficient expansion and differentiation of stem cell cultures.
  • Develop and implement enabling technologies that facilitate bioprocess automation, monitoring and control.
  • Design, plan, and execute R&D experiments that optimise unit operations and develop the over-arching bioprocess (from raw materials to final product), ensuring that deliverables are successfully met within timeline.
  • Analyse, summarise, record, and communicate experimental results. Document research findings clearly in an electronic lab book.
  • Along with team members, provide routine laboratory maintenance, including participating in equipment upkeep, cleaning rotas and laboratory consumables stock management.
  • Ensure that laboratory and workshop health, safety and quality procedures are followed.
  • Select, follow, and adapt experimental protocols and generate laboratory SOPs.
  • Support the preparation of laboratory risk assessments and maintenance of health and safety protocols.
  • Participate regularly in group meetings and prepare and deliver presentations to project team and internal stakeholders.

Qualifications:

Master or PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.

Experience in one or more of the following areas:

Essential Experience:

  • Two or more years' experience in upstream bioprocess development in an industrial or academic setting.
  • Experience in designing, developing and operating bioreactors.
  • Substantial experience in aseptic cell culture, ideally with stem cells.

Desirable experience:

  • Experience with adherent cell cultures is highly desirable
  • Experience with statistical software and DoE (design of experiments).
  • Appreciation of Quality by Design principles.
  • Ability to develop mechanical designs, PFD, P&IDs, HAZOP and SOPs.
  • Experience with CAD (e.g. Autodesk) and CFD (e.g. Ansys Fluent) software packages.
  • Ability to use a programming language (e.g. MATLAB, R) would be a bonus.


You must be eligible to work in the UK. Learn more

  • Agency: Cranleigh Scientific
  • Reference: 6818
  • Posted: 7th April 2021
  • Expires: 5th May 2021

Cranleigh Scientific

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