A growing start-up has an exciting opportunity for a Biochemical Engineer to join its team. As biochemical engineer, you will be developing the manufacturing process to produce tissue at large-scale. You will ideally be educated to PhD in Chemical Engineering, or a related subject, and have experience in upstream bioprocessing and in in designing, developing and operating bioreactors.
Position summary:
As a Biochemical Engineer in the Bioprocessing team you will be tasked with developing the manufacturing process to produce tissue at large-scale. Your duties will include:
- Design, build and operate bioreactor technology at the bench-scale to enable efficient expansion and differentiation of stem cell cultures.
- Develop and implement enabling technologies that facilitate bioprocess automation, monitoring and control.
- Design, plan, and execute R&D experiments that optimise unit operations and develop the over-arching bioprocess (from raw materials to final product), ensuring that deliverables are successfully met within timeline.
- Analyse, summarise, record, and communicate experimental results. Document research findings clearly in an electronic lab book.
- Along with team members, provide routine laboratory maintenance, including participating in equipment upkeep, cleaning rotas and laboratory consumables stock management.
- Ensure that laboratory and workshop health, safety and quality procedures are followed.
- Select, follow, and adapt experimental protocols and generate laboratory SOPs.
- Support the preparation of laboratory risk assessments and maintenance of health and safety protocols.
- Participate regularly in group meetings and prepare and deliver presentations to project team and internal stakeholders.
Qualifications:
Master or PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.
Experience in one or more of the following areas:
Essential Experience:
- Two or more years' experience in upstream bioprocess development in an industrial or academic setting.
- Experience in designing, developing and operating bioreactors.
- Substantial experience in aseptic cell culture, ideally with stem cells.
Desirable experience:
- Experience with adherent cell cultures is highly desirable
- Experience with statistical software and DoE (design of experiments).
- Appreciation of Quality by Design principles.
- Ability to develop mechanical designs, PFD, P&IDs, HAZOP and SOPs.
- Experience with CAD (e.g. Autodesk) and CFD (e.g. Ansys Fluent) software packages.
- Ability to use a programming language (e.g. MATLAB, R) would be a bonus.
You must be eligible to work in the UK. Learn more
- Agency: Cranleigh Scientific
- Reference: 6818
- Posted: 7th April 2021
- Expires: 5th May 2021
