Jason at CK Science is recruiting for a GMP Biotechnologist / Viral Vector Manufacturing Scientist to join a multinational clinical-stage cell & gene therapy research company focused on the development and commercialisation of gene therapies for debilitating disorders based on a next-generation AAV gene therapy platform. This is a permanent role based in Hertfordshire (20 minutes North of London via train) and offers an excellent salary c£35,000 and a good benefits package.
The organisation has a strong reputation for their technical and strategic expertise within the cell and gene therapy market across Europe and places a strong emphasis on innovation, ability to make a difference to the patients, as well as the ability to apply your skills and develop new ones by collaborating with a multidisciplinary team. They will provide you with promising and exiting research projects in an environment that strongly values your development. Their gene therapy treatment builds upon their own pioneering work and their proprietary AAV capsid which is optimised to effectively transduce human liver cells and thus provide sustainable, high levels of the desired protein.
As part of the GMP manufacturing operations team you will be responsible for delivering GMP manufacturing batches for clinical studies. You will be responsible for writing and reviewing SOPs, batch records, protocols, reports etc. to support GMP manufacture and will have the ability to identify issues as they occur & report accordingly with all relevant information. You will support investigations, OOS, incidents and CAPAs as required and will be part of the team responsible for technology transfer of the process into GMP according to the approved protocols. Working closely with facility and other supporting teams to ensure requirements for manufacture are met you will also be involved in the maintenance of clean room production facilities to GMP standards and the preparation of equipment, materials and facilities ready for GMP manufacture.
With a BSc degree in biological science you will have hands-on, practical experience in biological drug substance GMP manufacturing operations and a sound understanding of the required industry standards for GMP manufacturing of investigational medicinal products. You will have hands on experience in the upstream processing (USP) and/or downstream processing (DSP) for viral vector manufacturing along with hands on experience in aseptic cell culture processing for seed train expansion prior to USP. Experience in one or more of the following areas would be beneficial: facility operations, equipment qualification and validation, technology transfer, process validation. Experience and a technical understanding of AAV or other viral vector development/manufacture is preferred as is experience of GMP facility set up.
Please note that your CV should show exact dates of employment (month and year) and any gaps of a month or more should be explained.
CK Group is an Equal Opportunities employer and welcomes applications from all who meet our selection criteria.
If you do not hear back from us within 5 working days of your application for this role, it means that on this occasion you have not been shortlisted for the next stage of the recruitment campaign. Entitlement to work in the EEA is essential. Please quote reference 44399 in all correspondence.
You must be eligible to work in the UK. Learn more
- Agency: CK Group
- Contact: Jason Johal
- Phone: 01438 723 500
- Reference: 44399
- Posted: 7th May 2019
- Expires: 4th June 2019