Jason Johal is currently recruiting for an experienced Cell Biologist to join a dedicated team of Research Scientists providing an outsourced service to one of the top ten largest pharmaceutical companies in the world. This role is based at the client's research and development site in Surrey which is commutable from London, Oxford, Reading and Guilford and is offered on a permanent basis with a salary of £30,000 to £40,000.
The purpose of this role is to run cell-based functional assays in support of neuroscience drug discovery projects and to make a major contribution to neuroscience functional assay experimental platform development.
Key responsibilities will include but are not limited to:
· Maintenance and manipulation of human iPSC cells, differentiation into neurons and performing biochemical, imaging or functional assays in these cells
· Working with other cell systems, for example primary neuronal culture or immortalised cell lines and manipulations of these cells (e.g. viral transfection, siRNA knock-down, genetic manipulation, co-culture) to increase target validation for various molecular pathways
· Measurement of biochemical or functional parameters in cells using techniques including microscopy, live fluorescence imaging, immunocytochemistry, calcium imaging, morphology, live/dead cell assays
· Designing, validating, troubleshooting, and performing molecular, biochemical and cell-based assays, including high content imaging assays to address key molecular mechanisms and test new chemical entities
· Performing assays that might include: AlphaScreen, ELISA, MSD, SDS-PAGE
· Provide written and oral communication of work in lab reports and team meetings
· Accurate recording of all practical work: completion of electronic lab notebook to Lilly procedure quality standards
· Maintaining a tidy and efficient laboratory environment and ensuring health and safety standards are met
You are required to have the following qualifications, skills and experience:
· Hands-on experience in aseptic cell culture technique including iPSC culture
· Ability to analyse and interpret biochemical and cell-based imaging data and identify errors
· Capable of independently designing experiments, generating data, interpreting results and documenting work
· BSc/MSc with further experience or PhD in a neuroscience-related subject (or equivalent)
· Working knowledge of key biochemical techniques, cellular assays and cell biology
· Sound knowledge of experimental design and statistics for biology experimental work
· Understanding of biology lab safety requirements
Our client has 7,000 employees who work just within the Research Laboratories, spanning more than 50 countries worldwide and are the 7th largest investor in R&D in the UK within the pharmaceutical sector. The successful candidate will be a full-time fixed term employee of the CK Group and will be working for CK as part of a very busy, productive team of scientists that CK provide for our client as an outsourced function. As such they must be able to demonstrate enthusiasm, dedication and self-motivation together with the desire to acquire new skills.
Please note that your CV should show exact dates of employment (month and year) and any gaps of a month or more should be explained.
CK Group is an Equal Opportunities employer and welcomes applications from all who meet our selection criteria.
If you do not hear back from us within 5 working days of your application for this role, it means that on this occasion you have not been shortlisted for the next stage of the recruitment campaign. Entitlement to work in the EEA is essential. Please quote reference 45381 in all correspondence.
You must be eligible to work in the UK. Learn more
- Agency: CK Group
- Contact: Jason Johal
- Phone: 01438 723 500
- Reference: 45381
- Posted: 29th April 2019
- Expires: 27th May 2019