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Research Scientist I, Biomarker Development

Cambridgeshire   •  Negotiable  •  Permanent, Full time


If you are inspired by developing your career in a stimulating environment where you can make a profound difference to the healthcare of patients, my client can offer exceptional careers for exceptional people. Based on an established Bioscience campus in Cambridge, you will have the opportunity to work with smarter science, unique technologies and highly experienced scientific leaders.

The company is engaged in the discovery and development of human monoclonal antibody therapeutics using novel monoclonal antibody therapeutic platforms
They are looking to recruit an exceptional Research Scientist to join their Biomarker Development as part of their R&D Group.

Duties/Responsibilities:
Establish and deliver clinically relevant biomarker assays
Provide input into assay development strategies required for individual projects and the subsequent data analysis
Serve as lead biomarker scientist on some late stage projects to establish predictive biomarker hypotheses, including indication selection and markers of response.
Contribute to the strategic views and guidance on biomarker clinical plans using novel approaches and incorporating new technological capabilities
Design, develop, run or supervise in vitro primary cell based assays (Receptor occupancy, IHC assay, transcriptomic, cytokines analysis etc..) supporting the biomarker strategy of our clinical candidates for all of the companys therapeutic areas
Maintain laboratory notebooks to standard required for regulatory filings and publications. Develop and assist in documentation of novel IP related to biomarker discoveries (support patent filling)
Ability to oversee bio-sample management activities across multiple clinical trials.

Requirements:
Educated to MSc/PhD level in a relevant discipline (Immunology, Pharmacology or similar), with at least 2 years relevant postdoctoral or industry experience
Experience in clinical research or bio-sample handling within an industrial setting
Knowledge in molecular and cellular biology and immunology is key. Expertise in FACS, transcriptomics, IHC, multi-colour flow cytometry, human cellular assays
Knowledge of GLP environment and Hands-on experience in handling clinical biological samples would be an advantage
Effective team player and ability to collaborate with cross functional clinical study teams and external CROs.
Excellent written and interpersonal communication skills necessary to interface with outside vendors, consultants, and team members. Demonstrated strengths in planning, organisational, analytical skills, time management, problem solving, and attention to details.

Can you see yourself being part of a company that celebrates diversity and believes that better thinking and decisions come from wider experience? If the answer is yes and you have a desire to be an integral part of a dynamic team, we would be keen to hear from you. In the first instance, please send your CV to Matthew Walsh: matt@scientificprofessionals.com . We endeavour to come back to you within 24 hours of CV submission.

  • Agency: Clinical Professionals
  • Contact: Matthew Walsh
  • Reference: JO-1807-413384
  • Posted: 27th July 2018
  • Expires: 24th August 2018
Clinical Professionals

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